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  #11 (permalink)  
Old 08-17-2008, 2:56 PM
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"Development of breast cancer entails multiple events, in which estrogen appears to play an important role," explained Russo. "Our laboratory has pioneered an in vitro system of cell transformation using estrogens and their metabolites as carcinogenic agents in human breast cells. Our data show that each compartment of the breast has specific differentially expressed genes that provide a genomic signature according to the increasing maturation of the organ.


"Estrogenic agents involved in breast development and possibly in breast cancer may include foreign estrogens, or xenoestrogens, that are used in manufacturing a number of products. The studies of BPA and BBP in young rats were designed to see whether exposure to these hormonally active biological compounds could alter the genomic signatures of the mammary gland during critical stages of development."


BPA (bisphenol A) is a synthetic resin used in food packaging, dental sealants and polycarbonate plastic products, which range from CDs and eyeglass lenses to tableware and food and beverage containers, including baby bottles. BBP (n-butyl benzyl phthalate) is a widely used plasticizer used in food wraps and cosmetics.


"In exposing prepubescent female rats to BPA and BBP, our aim was to determine what effects, if any, each compound had on mammary gene expression during at different ages," said Moral.


"Our results showed that exposure to BPA changes the gene expression profile of mammary tissues as a function of age. That is, there was a significant increase in protein production governed by various genes at increasing ages from 21 to 100 days."


These included proteins regulating cell proliferation and differentiation, including tumor-suppressing proteins and a large number of unknown proteins. The exception was decreased expression of the GAD1 gene. It encodes a key enzyme of the GABA-ergic system, which could be involved in hormonal regulation and breast cancer development. GAD1 has consistently been overexpressed in primary breast cancer.
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Old 08-17-2008, 4:44 PM
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There are a several versions of this eRumor.

The first to appear on the Internet was a message that says a Dr. Edward Fujimoto from the Castle Hospital (no location mentioned) appeared on television and said plastic containers should not be used for heating foods in a microwave oven. He said this is especially true if the foods contain fat. The message claims that the combination of fats and plastics will release dioxins into the food and into the cells of the body with a risk of cancer. The doctor recommended using glass, Corning Ware, or ceramic containers instead in order to avoid the dioxin. Prepared foods such as TV dinners should be taken out of plastic containers before heating.

The second version tells the story of a seventh-grade student who decided to do some experiments with microwave radiation on food wrapped in plastic. She is said to have enlisted the help of the National Center for "Toxicological" Research in Arkansas. The student allegedly found that not only are there carcinogens migrating from the plastic into food during microwaving, but other substances as well.
This eRumor also lists an article about Dr. Edward Fujimoto saying that he appeared on a TV station in Huntsville, Alabama.

Another version claims all this was in newsletters from Johns Hopkins University and Walter Reed Army Medical center.

Yet another version says that singer Sheryl Crow, who is suffering from breast cancer, got her cancer from drinking from plastic water bottles left in the sun and that got too hot and, as a result, were contaminated with dioxins.



The Truth:
TruthOrFiction.com has not been able to find any research that supports the fear that food can become contaminated with dioxins either from plastic wrap or plastic in microwave ovens.

It's an understandable concern because dioxins are among the most poisonous chemical group known and steps have been taken by many world governments to reduce the amounts of dioxins in the environment.

Dr. Edward Fujimoto is real and is the Manager of the Wellness and Lifestyle Medicine Department at Castle Medical Center in Hawaii. (not Alabama). Part of this eRumor is the result of an interview he did on KHON-TV channel 2 in Hawaii on January 23, 2002.

TruthOrFiction.com contacted Dr. Fujimoto who said the eRumor quoted him fairly accurately. His concern was whether a combination of ingredients, especially plastics and food fats, could result in food being contaminated by dioxins when heated in a microwave. That is his observation and he claims to have research substantiating it.
TruthOrFiction.com has twice asked for him to give us that research but has never received it. He said that he is surprised about how little Americans know about dioxins in everyday life because in Japan, the majority of the population knows about them and the country has enacted regulations to protect its people. He explained that in his view, heating food in a plastic container will produce the release of dioxins and fat will absorb them. The amount of migration of dioxins to fat, he said, will be a function of the heat in the microwave, the type of plastic, the length of time of exposure, and the amount of fat that is in contact. Dr. Fujimoto pointed out that the amounts of dioxins in any given piece of plastic or food that is microwaved in plastic is very small, but that the problem is that dioxins get into the human body and accumulate. He sad that in Japan, there has been a complete change in the way foods are packaged so that plastic is avoided. They use more glass, for example.

In early 2004, a corrupted version of the eRumor started circulating that made it appear as though Dr. Fujimoto was also concerned about putting water in plastic bottles and freezing it, but he never addressed that. This version of the eRumor also made it sound as though the plastic itself was the problem, not the plastic in combination with food and heat. It says, for example, that the heat causes dioxin (sic) to "drip from the plastic" into the food but none of the researchers has claimed that.

A variation of the bottled water version said that was how singer Sheryl Crow got cancer, by drinking bottled water and that she appeared on the Ellen show or the Oprah show to tell the story. Crow has been treated for breast cancer but she's never blamed it on bottled water.

Another version of eRumor about the seventh-grader has been a little more difficult to detail. We've confirmed that there is a Dr. Jon Wilkes at the National Center for Toxilogical Research who, along with a Claire V. Nelson, published a paper at a professional event in Orlando, Florida in 1998 and it was on the subject of food contamination from plastic wrap. We've not found the actual study, however, and have never received a response from Dr. Wilkes. The eRumor about Jon Wilkes and Claire Nelson appears to have come from the Options Newsletter published by People Against Cancer at Cancer treatment, cancer cure, cancer therapy, cancer alternative medicine.

The folks who make Saran Wrap have responded to the eRumor. A statement by the SC Johnson company says the "plasticizer" in Saran Wrap is derivative of naturally occurring citric acid found in citrus fruits and is 100% dioxin free. The statement further adds that dioxins can only be formed with chlorine is combined with the kinds of high temperatures associated with waste incinerators, temperatures like 1,500 degrees F. Even the most powerful microwaves are not capable of those temperatures, according to the company.
SC Johnson says none of its products contains dioxins.

According to the U.S. Environmental Protection Agency, dioxins are both natural and man-made. The man-made dioxins are released into the air from sources like waste incineration, from burning fuels (like wood, coal or oil), and certain types of chemical processing. Almost every person has been exposed to low levels of dioxins and the EPA says there is research that suggests that high levels of dioxins may be correlated with various health problems, although some of that is extrapolated from studies of animals, not humans.

The only reference we could find about dioxins and microwaves was from an FDA publication that was concerned about dioxins resulting from the bleached manufacture of paper goods including milk cartons and some paper containers for microwave dinners. That was not about plastics and high temperatures, however, and the levels of dioxins were described as safe.

The Food and Safety Inspection Service of the U.S. Department of Agriculture has published guidelines for safe cooking in microwave ovens and warns against using materials that are not regarded as microwave safe. CLICK HERE for those guidelines. You'll note that one of the guidelines is to avoid letting plastic wraps touch food. That is another issue, however, and not related to dioxins or high heat in microwaves.

The Food and Drug Administration has also issued a statement about plastics and microwaves.vCLICK HERE for that document.

The American Plastics Council has also posted a page on the subject.
CLICK HERE for their take on the dioxin question.

Somewhere along the way someone decided to add that all this information had appeared in newsletters from Johns Hopkins University and Walter Reed Army Medical center but neither has promoted the dioxin story.

Even though Johns Hopkins has not been the source of the eRumor, there have been enough emails that falsely attributed the story to them that the Johns Hopkins Bloomberg School of Public Health asked Dr. Rolf Halden, a professor in the Department of Environmental Health Services at the school's Center for Water and Health to address the concerns over dioxins. He said that the principal sources of dioxins are from various combustion processes including natural events such as wild fires and volcanic eruptions. Plastics do not actually contain dioxins, he said, but wastes that contain certain compounds can serve as dioxin precursors when incinerated. According to Halden, most people are exposed to dioxins when eating meat and fish rich in fat because dioxins that have been sent into the atmosphere become attached to particles that fall back to the earth and get concentrated and store in the fat of fish and other animals.

Halden said that the alleged danger or freezing water in plastic bottles is unfounded and an urban legend. First, because there are no dioxins in plastics. Second because freezing actually inhibits the release of chemicals. He said people should be more concerned about the quality of the water in the bottles, not the bottles themselves. He added that there is another group of chemicals added to plastics to make them flexible and less brittle that could disrupt endocrine functions in humans and animals and that heating up the plastics could increase their being released into water and food.

Regarding cooking with plastics, Halden said that whenever you heat something it increases the likelihood that chemicals could be pulled out. he recommends using heat-resistant glass or ceramics for microwave cooking, just to be safe.

A real example of the eRumor as it has appeared on the Internet:
\
Example #1

On Channel 2 this morning. They had a Dr. Edward
Fujimoto from Castle Hospital on the program. He is the manager of the Wellness Program at the hospital. He was talking about dioxins and how bad they are for us.

He said that we should not be heating our food in the microwave using plastic containers. This applies to foods that contain fat. He said that the combination of fat, high heat and plastics releases dioxins into the food and ultimately into the cells of the body.

Dioxins are carcinogens and highly toxic to the cells of our bodies. Instead, he recommends using glass, Corning Ware, or ceramic containers for heating food. You get the same results without the dioxins. So such things as TV dinners, instant saimin and soups, etc. should be removed from the container and heated in something else.

Paper isn't bad but you don't know what is in the paper. Just safer to use tempered glass, Corning Ware, etc. He said we might remember when some of the fast food restaurants moved away from the foam containers to paper. The dioxin problem is one of the reasons.

Pass this on to your family and friends.

Example #2


As a seventh grade student, Claire Nelson learned
that di(ethylhexyl)adepate (DEHA), considered a
carcinogen, is found in plastic wrap. She also learned
that the FDA had never studied the effect of microwave
cooking on plastic-wrapped food.

Claire began to wonder: "Can cancer-causing particles
seep into food covered with household plastic wrap
while it is being microwaved?"

Three years later, with encouragement from her high
school science teacher, Claire set out to test what the
FDA had not. Although she had an idea for studying
the effect of microwave radiation on plastic-wrapped
food, she did not have the equipment. Eventually, Jon
Wilkes at the National Center for Toxicological Research
in Jeferson, Arkansas, agreed to help her. The research
center, which is affiliated with the FDA, let her use its
facilities to perform her experiments, which involved
microwaving plastic wrap in virgin olive oil.

Claire tested four different plastic wraps and "found not
just the carcinogens but also xenoestrogen was migrating
[into the oil].... " Xenoestrogens are linked to low sperm
counts in men and to breast cancer in women.

Throughout her junior and senior years, Claire made a
couple of trips each week to the research center, which
was 25 miles from her home, to work on her experiment.

An article in Options reported that "her analysis found
that DEHA was migrating into the oil at between 200 parts
and 500 parts per million. The FDA standard is 0.05 parts
per billion." Her summarized results have been published
in science journals. Claire Nelson received the American
Chemical Society's top science prize for students during
her junior year and fourth place at the International Science
and Engineering Fair (Fort Worth, Texas) as a senior.

"Carcinogens -- At 10,000,000 Times FDA Limits" Options
May 2000. Published by People Against Cancer, 515-972-4444

On Channel 2 (Huntsville, AL) this morning they had a
Dr. Edward Fujimoto from Castle Hospital on the program.
He is the manager of the Wellness Program at the hospital.
He was talking about dioxins and how bad they are for us.
He said that we should not be heating our food in the
microwave using plastic containers. This applies to foods
that contain fat. He said that the combination of fat, high heat
and plastics releases dioxins into the food and ultimately into
the cells of the body. Dioxins are carcinogens and highly
toxic to the cells of our bodies. Instead, he recommends
using glass, Corning Ware, or ceramic containers for heating
food. You get the same results without the dioxins.

So such things as TV dinners, instant saimin and soups, etc.,
should be removed from the container and heated in
something else. Paper isn't bad but you don't know what is
in the paper. Just safer to use tempered glass, Corning Ware,
etc.

He said we might remember when some of the fast food
restaurants moved away from the foam containers to paper.
The dioxin problem is one of the
reasons.

To add to this: Saran wrap placed over foods as they are nuked,
with the high heat, actually drips poisonous toxins into the food.
Use paper towel instead.

Pass this on to your friends...



Example #3

This is how Sheryl Crow got breast cancer she was on the Ellen show and She said this same exact thing. The doctor told her: women should not drink bottled water that has been left in a car. The doctor said that the heat and the plastic of the bottle have certain chemicals that can lead to breast cancer. The heat causes toxins from the plastic to leak into the water and they have found these toxins in breast tissue.
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  #13 (permalink)  
Old 08-27-2008, 1:53 AM
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"AVOID PLASTICS GET A GREENER AND A CLEANER ATMOSPHERE"....This ia a slogan which everyone should follow to have a cleaner and greener atmosphere ..
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  #14 (permalink)  
Old 08-27-2008, 1:54 AM
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Plastics spread alien species: far from destroying marine life, rubbish is causing alien species to proliferate, putting native species in many parts of the world at risk. (worldwatch: polar collection sold at auction * BP conservation awards news * predicting volcanic eruptions * ocean litter threatens biodiversity).(Brief Article)
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  #15 (permalink)  
Old 08-28-2008, 1:38 AM
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The bottles are safe for one-time use only; if you must keep them longer, it should be or no more than a few days, a week max, and keep them away from heat as well. Repeated washing and rinsing can cause the plastic to break down and the carcinogens (cancer- causing chemical agents)can leach into the water that YOU are drinking. Better to invest in water bottles that are really meant for multiple uses.
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  #16 (permalink)  
Old 08-28-2008, 1:44 AM
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Having read that plastics are bad for health during her days as an undergraduate in chemical engineering, her mother-in-law's cancer brought home the message of the importance of health.Bisphenol-A is a chemical found in plastic baby bottles, microwaveable plastic food containers and the lining of tin cans containing food and drinks.
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  #17 (permalink)  
Old Yesterday, 6:25 AM
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Indeed plastics are harmful to the environment hence disposing properly is very important. It's highly impossible for us to stop using plastics immediately since many products we use comes along with plastics. But as the time moves on gradually we should stop using the plastics.
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